A Kerberos server will reject ticket requests from a client whose clock isn't within the specified maximum clock skew of the KDC.
You must synchronize your system clock with the KDC server clock. The default maximum allowed time skew is 5 minutes.
TSIG signatures also require time synchronization. TSIG signatures are time-stamped and only valid within a short time period. Therefore, Windows Active Directory and BlueCat DNS server must be in synchronization.